Natural products are bioactive compounds synthesized by terrestrial and marine plants, microorganisms and animals, whose main objective is to prevent them from attacks by predators and/or pathogens. Traditionally since ancient times, different cultures have used these compounds for the prevention and treatment of various human diseases. During the last few years, it has been reported that most of these phytochemicals possess a variety of interesting and significant biological properties, such as analgesic, antiallodynic, antidiabetic, antioxidant, antiparasitic, antimicrobial, antiviral, antiatherogenic, anti-inflammatory, antiproliferative, antitumor and normal growth stimulants, as well as significant cardioprotective and neuroprotective activity. This thematic book aims to collect and disseminate some of the most significant and recent contributions of the use of the natural compounds called phytochemicals, as well as some of their chemical derivatives, for the prevention and treatment of cancer and other accompanying diseases. On the other hand, in recent years, the synthesis of numerous chemical derivatives of these natural compounds has also intensified, with the aim of enhancing their bioactive capacities. Among all these bioactivities, special attention has been paid to its antitumor capacity through the potential modulation of cancer initiation and growth, cell differentiation, apoptosis and autophagy, angiogenesis, and metastatic dissemination. In addition, a considerable number of studies have linked their anticancer effects to their anti-inflammatory and antioxidant activities.

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Phenolic compounds are non-essential dietary compounds that are found in many vegetables (i.e. onion, cabbage, broccoli and parsley), fruits (i.e. cherries, grapes, berries and pears), cereals and beverages (i.e. red wine, tea and chocolate). These heterogeneous compounds are produced as secondary metabolites. Structurally, these compounds are characterized by comprising an aromatic ring with one or more hydroxyl groups that can be classified into two groups: flavonoids and non-flavonoids. Phenolic compounds have received considerable attention for its health-promoting properties in many chronic disorders including diabetes, cardiovascular diseases, cancer and neurodegenerative diseases, among others. These health benefits are mainly attributed to its antioxidant properties. Phenolic compounds act as antioxidant by scavenging free radicals, metal chelation and endogenous antioxidant system upregulation (enzymatic antioxidants such as catalase, superoxide dismutase and glutathione peroxidase and non-enzymatic antioxidants such as glutathione).The consumption of exogenous medicinal plants and food rich in phenolic compounds represent a promising therapeutically to prevent many chronic diseases and improve health.This Special Issue entitled “Effect of Phenolic Compounds on Human Health” include research articles and review articles on phenolic compounds and its role in health (i.e. flavonoids and diabetes, polyphenols and liver diseases, polyphenols and obesity, polyphenols and cardiovascular diseases and polyphenols and neuroprotection).

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Phytochemicals from natural products are now widely used as food additives (antioxidants, pigments), food supplements, cosmetic ingredients, etc. Currently, the majority of the extraction processes implemented on an industrial scale for the production of bioactive-enriched extracts are based on solvents of petroleum origin. However, contemporary trends in green extraction techniques dictate a minimization of solvent use, low-energy processes and novel eco-friendly materials that are environmentally benign. The search for liquids and/or extraction technologies that could meet such requirements is, therefore, an intriguing concept. This book addresses the concept of recovering natural bioactive substances from plant resources, using state-of-the-art extraction technologies, with prospects in the food, cosmetic and pharmaceutical industries.

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The seeds and fruits (or their parts) of IberoAmerican crops have high nutritional and functional properties that could be utilized in a wide range of foods. The crops included in this book are amaranth (Amaranthus spp.), quinoa (Chenopodium quinoa), kañiwa (Chenopodium pallidicaule), chia (Salvia hispanica L.), Andean maize (Zea mays L.), moringa (Moringa oleifera), broad beans (Vicia faba L.), kurugua (Sicana odorifera), sacha inchi (Plukenetia huayllabambana), and tarwi (Lupinus mutabilis), all of which are still underutilized. Their cultivation is low; nevertheless, in recent years, worldwide demand of some of them has increased immensely, resulting in an increase in their production. Ancient IberoAmerican crops have been widely recognized for their nutritional value by food scientists and food producers because they contain high-quality proteins, large quantities of micronutrients such as minerals and vitamins, and bioactive compounds. Moreover, they are gluten-free, which makes them suitable for people suffering from various gluten intolerances. This book summarizes the large amount of investigations in this field in the recent years and provides knowledge of all the relevant areas of food science. The editors hope that this book will contribute to their increased use in human nutrition by consumers worldwide.

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The book entitled Medicinal Plants and Natural Product Research describes various aspects of ethnopharmacological uses of medicinal plants; extraction, isolation, and identification of bioactive compounds from medicinal plants; various aspects of biological activity such as antioxidant, antimicrobial, anticancer, immunomodulatory activity, etc., as well as characterization of plant secondary metabolites as active substances from medicinal plants.

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This book was devoted to the latest advances achieved in the antibacterial field, with a focus on the recent efforts made to develop new antimicrobial agents with novel modes of action, and a perspective on future directions of this line of research. Antimicrobial resistance has become a major threat to global health, and the twenty-two published articles here reported put in evidence that the discovery and development of new antibiotics are extremely challenging. The antimicrobial research covers a wide area, spanning from the design of new compounds, also supported by molecular modeling techniques, their synthesis and characterization, and biological tests.In this context, the current crisis caused by the COVID-19 pandemic, but also older threats, such as the human immunodeficiency virus or the hepatitis C virus, require greater attention than ever.The research works described in this book provide an extremely useful example of the results achieved in the field of antibacterial drug development. The search for new chemical entities was approached starting from both natural and synthetic compounds and addressing different targets. In addition, recent findings were presented and discussed highlighting the strategies to fight bacterial resistance. Detailed references to the state-of-the-art can be found in this book.We strongly encourage the wide group of readers to explore the book that we are presenting, to get inspired to develop new approaches for the diagnosis and treatment of antibacterial diseases, and to circumvent resistance issues.

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Interest has grown regarding natural plant extracts in food and beverage applications, their vital role in the food industry, and their therapeutic use against diseases. The protective effects of healthy diets are partially due to the variety of plant metabolites, particularly phenolic compounds, which are considered the most important class of compounds that originates from plant-derived metabolites. Phenolics are well renowned for their possession of a wide array of remarkable biological properties. This Special Issue (SI) aims to gather the most recent contributions concerning their chemistry, extraction methods, and analytical techniques, applications, and biological activities. This Special Issue of Processes, entitled “Phenolic Compounds: Extraction, Optimization, Identification and Applications in Food Industry”, gathers the recent work of leading researchers in a single collection, covering a variety of theoretical studies and experimental applications and focusing on the extraction, identification, and industrial applications. The advances presented in the contributions in this SI have significantly helped to accomplish this target. In addition to research articles, the Special Issue features two reviews that cover a range of topics highlighting the versatility of the area. The topics covered in this SI include advanced methodologies for the isolation, purification, and analysis of phenolics from food, food waste, and medicinal plants; biological activities and mechanisms of action; health benefits from in vivo evaluation; and the development of novel phenolics-based nutraceuticals and functional ingredients.

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This Special Issue provides recent advances in the use of plants for therapeutic purposes. This Special Issue collected the plants, including leaf, fruit, and others. This Special Issue's targets were crude plant extract and active principle purified from the plant. This Special Issue prompted researchers to provide each plant discovery. We are pleased to include in this Special Issue the screened Mexican plants and the halophytic plants growing in central Saudi Arabia, and so on. As a result, we have sparked scientists' interest in studying the plant for therapeutic purposes. This field necessitates network pharmacology analysis and machine-aided learning. Many disorders resistant to modern medication are looking for active principles isolated from the plants all over the world.

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The aim of this Special Issue is to publish high quality papers concerning poultry nutrition and the interrelations between nutrition, metabolism, microbiota and the health of poultry. Therefore, I invite submissions of recent findings, as original research or reviews, on poultry nutrition, including, but not limited to, the following areas: the effect of feeding on poultry meat end egg quality; nutrient requirements of poultry; the use of functional feed additives to improve gut health and immune status; microbiota; nutraceuticals; soybean meal replacers as alternative sources of protein for poultry; the effects of feeding poultry on environmental impacts; the use of feed/food by-products in poultry diet; and feed technology.

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Increased consumer awareness of the effects of food in preventing nutrient-related diseases and maintaining physical and mental well-being has made nutritional improvement an important goal for the food and beverage industry, including the cereal sector. The Book “Qualitative and Nutritional Improvement of Cereal-Based Foods and Beverages” collects research articles aimed at exploring innovative ways to improve cereal-based foods and beverages; an old—if not ancient—group of products which are still on our table every day. The main directions of research aimed at nutritional improvement have to face either excess or deficiency in the diet. To this end, different strategies may be adopted, such as the reformulation of products, the introduction of functional ingredients, and the application of biotechnologies to increase the bioavailability of bioactive compounds. These interventions, however, can alter the physico-chemical and sensory properties of final products, making it necessary to achieve a balance between nutritional and quality modification. This book offers readers information on innovative ways to improve cereal-based foods and beverages, useful for researchers and for industry operators.

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The book ""Quality and Production of Forage"" is intended to keep readers updatedon the developments occurring in this field. As it is apparent that livestockanimals are important throughout the world because of the meat, milk and eggthey produce, knowledge about the forages available to animals must also beconsidered for increased production, quality and efficiency. This book providesinformation that readers will find considerably invaluable about forage feeds, suchas grass, legumes, and straw. The book is composed of ten papers, focusing on awide range of research activities and topics that feature the following concepts offorage: the effect of conservation method on forage protein value; Microbial thecomposition and mycotoxin content in forage; genetic diversity of forages; timelysowing to maximize yield for both grain and biomass; ensiling treatments onforage quality; the qualitative characteristics of different accessions of new foragespecies; forage policy influencing feed costs; feeding forage on animal health;high-protein tropical forages as alternative sources for poultry; impact of foragesin poultry diet and significance of forages in sustainable poultry productionsystems. This book will be an invaluable reference for students and professionalsin agricultural science and grassland and animal husbandry researches.

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Ruminants contribute significantly to human food security. However, the production of ruminants contributes to greenhouse gas (GHG) emissions that are responsible for climate change. GHGs such as methane, carbon dioxide, and nitrous oxide are produced from different processes of ruminant production. Ruminant enteric methane is a substantial component of methane produced by agriculture. This book presents novel and established methods in quantifying and reducing enteric methane emission from ruminants in different production systems. The book covers different types of ruminants including cattle, sheep, and goats. The chapters are contributed by scientists and authors from different parts of the world, demonstrating the importance of this problem and the universal drive for immediate and sustainable solutions. Although, biologically speaking, the production of enteric methane cannot be reduced to zero, high emissions are an indicator of inefficient digestion of feed in the rumen and low utilisation of feed energy. By presenting research that could lead to robust and yet practical quantification methods and mitigation strategies, this book not only contributes to the discourse and new knowledge on the magnitude of the problem but also brings forward potential solutions in different livestock production systems.

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Textiles are commonly constituted of natural and synthetic fibers for normal applications. To impart functional or aesthetic effects on the textiles, the surface characteristics in the fiber play an important role. Therefore, surface treatment or modification is a possible way to provide value-added properties to textiles. The textile material/fiber surface can be treated or modified physically and/or chemically to achieve different desired effects. This book will provide an open forum to draw the attention of academic researchers and industrial experts to looking into different aspects of the surface treatment of textiles.

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Developing sustainable organic agriculture and resilient agribusiness sector is fundamental, keeping in mind the value of the opportunity presented by the growing demand for healthy and safe food globally, with the expectation for the global population to reach 9.8 billion by 2050, and 11 billion by 2100.Lately, the main threats in Europe, and worldwide, are the increasingly dynamic climate change and economic factors related to currency fluctuations. While the current environmental policy provides several mechanisms to support agribusinesses in mitigating organic food for daily increasing human population and stability of the currency, it does not contemplate the relative readiness of individuals and businesses to act correctly.Organic farming is the practice that relies more on using sustainable methods to cultivate crops and produce food animals, avoiding chemicals and dietary synthetic drug inputs that do not belong to the natural ecosystem. Organic agriculture can also contribute to meaningful socioeconomic, ecologically sustainable development, and significantly in the development of the agribusiness sector, especially in developing countries.

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This book examines the state-of-the-art water and wastewater treatment methods that can be applied to develop a sustainable treatment technique in the future. Of the several high-quality articles submitted, twelve were published after the peer-review process, with an acceptance rate of 59 percent. In the first section of this book, the articles include the occurrence and removal of emerging contaminants in water bodies. Moreover, the presence of perfluoroalkyl and polyfluoroalkyl substances (PFASs) in water sources is discussed in detail. Subsequently, the removal of polycyclic aromatic hydrocarbons (PAHs), pharmaceuticals and personal care products (PPCPs), and dye with different physicochemical methods is investigated. In another section of this book, the removal of ammonia with anaerobic ammonium oxidation (anammox) is studied. Additionally, the elimination of heavy metals using the adsorption process, as an effective method, is discussed. Moreover, the performance of membrane bioreactors in the elimination of pollutants from landfill leachate is investigated in another article in this book. In addition to this, green and sustainable wastewater technologies (GSWTs) have recently attracted the attention of researchers. Therefore, nanoremediation and microalgae-based systems are discussed as the GSWTs.

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Clean water is one of the most important natural resources on earth. Wastewater, which is spent water, is also a valuable natural resource. However, wastewater may contain many contaminants and cannot be released back into the environment until the contaminants are removed. Untreated wastewater and inadequately treated wastewater may have a detrimental effect on the environment and has a harmful effect on human health. Water quality engineering addresses the sources, transport and treatment of chemical and microbiological contaminants that affect water. Objectives for the treatment of wastewater are that the treated wastewater can meet national effluent standards for the protection of the environment and the protection of public health. This book, which is based on the Special Issue, includes contributions on advanced technologies applied to the treatment of municipal and industrial wastewater and sludge. The book deals with recent advances in municipal wastewater, industrial wastewater, and sludge treatment technologies, health effects of municipal wastewater, risk management, energy efficient wastewater treatment, water sustainability, water reuse and resource recovery.

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